Faculty of Information Technology, BUT

Product Details

pqsfinder: an R/Bioconductor package for identification of potential quadruplex forming sequences

Created: 2016

Czech title
pqsfinder: R/Bioconductor balíček pro identifikaci sekvencí tvořících kvadruplexy
Type
software
License
optional - free
Authors
Hon Jiří, Ing. (DIFS FIT BUT)
Lexa Matej, Ing., Ph.D. (FI MUNI)
Martínek Tomáš, Ing., Ph.D. (DCSY FIT BUT)
Zendulka Jaroslav, doc. Ing., CSc. (DIFS FIT BUT)
Keywords
G-quadruplex; quadruplex; DNA; R; Bioconductor; pattern matching; searching; annotation
Description
The main functionality of the this package is to detect DNA sequence patterns that are likely to fold into an intramolecular G-quadruplex (G4). Unlike many other approaches, this package is able to detect sequences responsible for G4s folded from imperfect G-runs containing bulges or mismatches and as such is more sensitive than competing algorithms.
Location
Licence
Free software under the terms of BSD license (see http://www.opensource.org/licenses/bsd-license.php).
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