Thesis Details
Vyhledávání příbuzných proteinů s modifikovanou funkcí
Protein engineering is a young dynamic discipline with great amount of potential practical applications. However, its success is primarily based on perfect knowledge and usage of all existing information about protein function and structure. To achieve that, protein engineering is supported by plenty of bioinformatic tools and analysis. The goal of this project is to create a new tool for protein engineering that would enable researchers to identificate related proteins with modified function in still growing biological databases. The tool is designed as an automated workflow of existing bioinformatic analyses that leads to identification of proteins with the same type of enzymatic function, but with slightly modified properties - primarily in terms of selectivity, reaction speed and stability.
related protein identification, protein function prediction, bioinformatics
Bartík Vladimír, Ing., Ph.D. (DIFS FIT BUT), člen
Martínek Tomáš, doc. Ing., Ph.D. (DCSY FIT BUT), člen
Meduna Alexander, prof. RNDr., CSc. (DIFS FIT BUT), člen
Steingartner William, Ing., Ph.D. (TUKE), člen
Zbořil František, doc. Ing., Ph.D. (DITS FIT BUT), člen
@mastersthesis{FITMT17337,
author = "Ji\v{r}\'{i} Hon",
type = "Master's thesis",
title = "Vyhled\'{a}v\'{a}n\'{i} p\v{r}\'{i}buzn\'{y}ch protein\r{u} s modifikovanou funkc\'{i}",
school = "Brno University of Technology, Faculty of Information Technology",
year = 2015,
location = "Brno, CZ",
language = "czech",
url = "https://www.fit.vut.cz/study/thesis/17337/"
}