Project Details

PGine: Py/Bioconda software package for calculation of polygenic risk score in plants

Project Period: 1. 3. 2023 - 31. 12. 2023

Project Type: grant

Code: FEKT/FIT-J-23-8274

Agency: Brno University of Technology

Program: Vnitřní projekty VUT

Czech title

PGine: Softwarový balík Py/Bioconda pro výpočet skóre polygenního rizika u rostlin

Type

grant

Keywords

Polygenic Risk Score, Genetic Prediction, 1001 Genomes, Central Molecular Dogma, Arabidopsis thaliana

Abstract

The most important scientific challenges connect to climate change. Prediction algorithms take an important role, including improving plant breeding according to new environmental conditions. Therefore, this project focuses on calculating human disease probability based on genotype information polygenic risk score. This project's main goal is to adapt these algorithms to plant data in functional software. The software can be used to bring new insights into plant breeding and thus uncover possible solutions to the climate crisis.

Team members

Schwarzerová Jana, Ing. et Ing., MSc (FEKT VUT) , research leader
Hurta Martin, Ing. (UPSY FIT VUT)
Sekanina Lukáš, prof. Ing., Ph.D. (UPSY FIT VUT)