Course details

Advanced Bioinformatics

PBI Acad. year 2010/2011 Winter semester 4 credits

Current academic year

Guarantor

Lexa Matej, Ing., Ph.D.

Language of instruction

Czech

Completion

Examination

Time span

  • 20 hrs lectures
  • 13 hrs pc labs
  • 6 hrs projects

Department

Department of Computer Systems (UPSY)

Study literature

  • Jones N.C., Pevzner P.: An introduction to algorithms in bioinformatics. MIT Press, 2004, ISBN 978-0262101066

Syllabus of lectures

  1. Introduction
  2. Primary and derived bioinformatic data
  3. Statistical, information-theory and linguistic aspect of data
  4. Genomes and genome analysis methods
  5. Uniprot and sequence analysis methods
  6. Coding algorithms for biological sequence analysis
  7. PDB and structural data analysis
  8. Gene Ontology and functional data analysis
  9. Integration of data from multiple sources for genomics and proteomics
  10. Tools and libraries for software development (Biopython)
  11. Visualization tools (PyMol)
  12. Bioinformatics and nanotechnology: DNA computing, sequencing by hybridization
  13. Recent trends

Syllabus of computer exercises

  1. Biological sequence analysis (Bioperl, C/C++)
  2. Other methods of sequence analysis
  3. Biopython
  4. PyMol
  5. Integration of bioinformatic data

Course inclusion in study plans

  • Programme IT-MGR-2, field MBI, 2nd year of study, Compulsory
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