Course details
Bioinformatics
IV108 Acad. year 2011/2012 Winter semester
An advanced course in bioinformatics (lecture and computer lab) building upon elementary mol.biology and/or bioinformatics courses.
Guarantor
Language of instruction
Completion
Time span
- 13 hrs lectures
- 13 hrs exercises
Department
Subject specific learning outcomes and competences
Item has no knowledges.
Learning objectives
Item has no goals.
Prerequisite knowledge and skills
There are no prerequisites
Syllabus of lectures
1. Biological language (sequence segmentation, information-statistical analysis of biological sequences)
2. Pattern matching (algoritms based on filtration and suffix arrays)
3. Heuristic algorithms for similarity searching in biological sequences (BLAST, BLAT, Pattern Hunter)
4. Regular expressions in bioinformatics
5. Algorithms for analysis and prediction of structural data (secondary strukture, contacts inb proteins, domain identification)
6. Algorithms for analysis and prediction of structural data (3D structure, structural comparisons)
7. Working with molecular structures in Pymol
8. New methods of DNA sequencing
9. Genome assembly and other operations on short nucleic acid sequences
10. Prediction of melting temperature in DNA and other nucleic acids (program mfold)
11. RNA secondary structure
12. DNA computing
13. Comparative genomics of human (analysis of scientific papers)
Progress assessment
Study evaluation is based on marks obtained for specified items. Minimimum number of marks to pass is 50.
Controlled instruction
There are no checked study.