Product Details

PredictSNP: Robust and Accurate Consensus Classifier for Prediction of Disease-Related Mutations

Created: 2013

Czech title
PredictSNP: robustní a přesný klasifikátor pro predikci mutací asociovaných se vznikem onemocnění
Type
software
License
Use of the result by another entity is possible without acquiring a license in some cases
License Fee
The licensor does not require a license fee for the result
Authors
Bendl Jaroslav, Ing., Ph.D.
Štourač Jan
Šalanda Ondřej, Ing.
Pavelka Antonín
Wieben Eric
Zendulka Jaroslav, doc. Ing., CSc. (UIFS)
Brezovský Jan
Damborský Jiří, prof. Mgr., Dr. (UMEL)
Keywords

SNP, single nucleotide polymorphism, SNV, single nucleotide variant, pathogenicity prediction, disease-related mutations

Description

Thistool estimates the effect of amino acid substitutions on proteinfunction. The predictions are based on the results of the existingtools MAPP, PhD-SNP, PolyPhen-1, PolyPhen-2, SIFT and SNAP. Theprinciple of consensual approach is described in: "Bendl et. al.(2014) PredictSNP: Robust and Accurate Consensus Classifier forPrediction of Disease-Related Mutations. PLoS Computational Biology,10.". The user interface shows not only the overall results and theresults of underlying tools but also the experimental annotationsextracted from PMD and Uniprot databases.

Location

http://loschmidt.chemi.muni.cz/predictsnp/

License Conditions

The tool is freely available for the academic community. It cannot be used for commercial purposes (to protect the rights of third parties - integrated methods with non-free licence).

Files
Departments
Department of Information Systems (DIFS)
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