Result Details
Computational molecular evolution - from mathematical models to novel distance metric based on intra-group analysis
In the proposed paper we analyse and discuss the molecular evolution from the point of view of mathematical analysis and statistics. Some characteristics of distance-based algorithms for phylogenetic inference are depicted. We furthermore use knowledge of mathematical models to design a modified algorithm for phylogenetic tree reconstruction. We implement the presented methods in the form of a simple phylogenetic library, briefly report about results of our case study and finally show a way for building a web interface for biological purposes through Mobyle portal. Finally, we draw a conclusion and discuss possible future work on the project.
phylogeny, intra-group analysis, substitution model, Markov chains
@inproceedings{BUT76292,
author="Ivan {Vogel} and Pavel {Očenášek} and František {Zedek}",
title="Computational molecular evolution - from mathematical models to novel distance metric based on intra-group analysis",
booktitle="EDS '11 IMAPS CS International Conference Proceedings",
year="2011",
pages="264--269",
publisher="Brno University of Technology",
address="Brno",
isbn="978-80-214-4303-7"
}