Result Details

Metallomics study of lead-protein interactions in egg albumen by electrochemical and electrophoretic methods

HYNEK, D.; KREJČOVÁ, L.; KŘÍŽKOVÁ, S.; RUTTKAY-NEDECKÝ, B.; PIKULA, J.; ADAM, V.; HÁJKOVÁ, P.; TRNKOVÁ, L.; SOCHOR, J.; POHANKA, M.; HUBÁLEK, J.; BEKLOVÁ, M.; VRBA, R.; KIZEK, R. Metallomics study of lead-protein interactions in egg albumen by electrochemical and electrophoretic methods. International Journal of Electrochemical Science, 2012, vol. 7, no. 2, p. 943-964. ISSN: 1452-3981.
Type
journal article
Language
English
Authors
Hynek David, Ing. et Ing., Ph.D., CEITEC (CEITEC), UMEL (FEEC)
Krejčová Ludmila, MVDr., Ph.D., CEITEC (CEITEC), RG-1-02 (CEITEC)
Křížková Soňa, Ing., Ph.D., CEITEC (CEITEC), UMEL (FEEC)
Ruttkay-Nedecký Branislav, Ing. Dr. Techn., CEITEC (CEITEC), UMEL (FEEC)
PIKULA, J.
Adam Vojtěch, prof. RNDr., Ph.D., CEITEC (CEITEC), UBMI (FEEC), UMEL (FEEC)
HÁJKOVÁ, P.
Trnková Libuše, prof. RNDr., CSc., CEITEC (CEITEC)
Sochor Jiří, doc. Ing., Ph.D., CEITEC (CEITEC), RG-1-02 (CEITEC), UBMI (FEEC), UMEL (FEEC)
Pohanka Miroslav, prof. RNDr., Ph.D., DSc.
Hubálek Jaromír, prof. Ing., Ph.D., CEITEC (CEITEC), UMEL (FEEC)
Beklová Miroslava, prof. RNDr., CSc., CEITEC (CEITEC), UBMI (FEEC), UMEL (FEEC), VHK (FCE)
Vrba Radimír, prof. Ing., CSc., CEITEC (CEITEC), RG-2-02 (CEITEC), UMEL (FEEC)
Kizek René, prof. Ing., Ph.D., CEITEC (CEITEC), UBMI (FEEC), UMEL (FEEC)
Abstract

Lead(II) ions represent still threath to living organisms due to high burden of these ions in environment. The aim of this study was to design and perform experiments studying the interaction of lead(II) ions and proteins contained in egg albumen. For this purpose, we used electrochemical and electrophoretic techniques. The results bring new and unique point of view in metallomics research and may provide new insights into mechanisms duringembryonic development.

Keywords

protein interaction, automated electrochemical detection; differential pulse voltammetry; heavy metal; capillary electrophoresis; metallothionein; spectrophotometry; proteomics

Published
2012
Pages
943–964
Journal
International Journal of Electrochemical Science, vol. 7, no. 2, ISSN 1452-3981
UT WoS
000302730000004
BibTeX 
@article{BUT75744,
  author="HYNEK, D. and KREJČOVÁ, L. and KŘÍŽKOVÁ, S. and RUTTKAY-NEDECKÝ, B. and PIKULA, J. and ADAM, V. and HÁJKOVÁ, P. and TRNKOVÁ, L. and SOCHOR, J. and POHANKA, M. and HUBÁLEK, J. and BEKLOVÁ, M. and VRBA, R. and KIZEK, R.",
  title="Metallomics study of lead-protein interactions in egg albumen by electrochemical and electrophoretic methods",
  journal="International Journal of Electrochemical Science",
  year="2012",
  volume="7",
  number="2",
  pages="943--964",
  issn="1452-3981"
}
Departments
Department of Microelectronics (UMEL)
Smart Nanodevices (RG-1-02)
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