Faculty of Information Technology, BUT

Publication Details

FireProt: web server for automated design of thermostable proteins

MUSIL Miloš, MARTÍNEK Tomáš and ZENDULKA Jaroslav. FireProt: web server for automated design of thermostable proteins. In: DAZ & WIKT 2018 Proceedings. Brno, 2018, pp. 1-4.
Type
conference paper
Language
english
Authors
Annotation
There is a continuous interest in increasing proteins stability to enhance their usability in numerous biomedical and biotechnological applications. Only a single-point mutations with a small impact on protein stability are typically predicted with the existing tools, while more complex multiple-point mutants are necessary for useful stabilization. Here, we present FireProt, a web server for automated design of multiplepoint thermostable mutants that combines structural and evolutionary information in its calculation core. The server is complemented with interactive, easy-to-use interface that allows users to directly analyze and optionally modify designed thermostable mutants.
Published
2018
Pages
1-4
Proceedings
DAZ & WIKT 2018 Proceedings
Conference
Data a znalosti 2018, Brno, CZ
Place
Brno, CZ
BibTeX
@INPROCEEDINGS{FITPUB11818,
   author = "Milo\v{s} Musil and Tom\'{a}\v{s} Mart\'{i}nek and Jaroslav Zendulka",
   title = "FireProt: web server for automated design of thermostable proteins",
   pages = "1--4",
   booktitle = "DAZ \& WIKT 2018 Proceedings",
   year = 2018,
   location = "Brno, CZ",
   language = "english",
   url = "https://www.fit.vut.cz/research/publication/11818"
}
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