Result Details
Computational molecular evolution - from mathematical models to novel distance metric based on intra-group analysis
Očenášek Pavel, Mgr. Ing., Ph.D., DIFS (FIT)
Zedek František
In the proposed paper we analyse and discuss the molecular evolution from the point of view of mathematical analysis and statistics. Some characteristics of distance-based algorithms for phylogenetic inference are depicted. We furthermore use knowledge of mathematical models to design a modified algorithm for phylogenetic tree reconstruction. We implement the presented methods in the form of a simple phylogenetic library, briefly report about results of our case study and finally show a way for building a web interface for biological purposes through Mobyle portal. Finally, we draw a conclusion and discuss possible future work on the project.
phylogeny, intra-group analysis, substitution model, Markov chains
@inproceedings{BUT76292,
author="Ivan {Vogel} and Pavel {Očenášek} and František {Zedek}",
title="Computational molecular evolution - from mathematical models to novel distance metric based on intra-group analysis",
booktitle="EDS '11 IMAPS CS International Conference Proceedings",
year="2011",
pages="264--269",
publisher="Brno University of Technology",
address="Brno",
isbn="978-80-214-4303-7"
}