Thesis Details

Analýza genomických dat s využitím algoritmu BLAST

Bachelor's Thesis Student: Křížová Martina Academic Year: 2007/2008 Supervisor: Jaša Petr, Ing.
English title
Analysis of Genomic Data with the Assistance of Algorithm BLAST
Language
Czech
Abstract

This Bachelor Thesis describes analysis of genomic data with assistance of algorithm BLAST. In theoretic part, it describes genomes, their importance and structure. In this thesis, you can find a description of algorithm BLAST, Smith-Waterman and Needleman-Wunsch and with algorithm BLAST connected Karlin-Altschul statistics. This thesis is discussing types of databases such as spatial, deductive and relational which store genomic data. Second part is concerned with design and implementation of application which use mentioned algorithm and database Oracle 10g R2. Testing and confrontation output of algorithm is also a part of this work.

Keywords

Genetics, DNA, protein, BLAST, Smith-Waterman, Needleman-Wunsch, substitution matrix BLOSUM, PAM, theory Margaret Dayhoff, Karlin-ALtschul statistics, Oracle 10g

Department
Degree Programme
Information Technology
Files
Status
defended, grade B
Date
26 August 2008
Reviewer
Committee
Švéda Miroslav, prof. Ing., CSc. (DIFS FIT BUT), předseda
Křena Bohuslav, Ing., Ph.D. (DITS FIT BUT), člen
Lukáš Roman, Ing., Ph.D. (DIFS FIT BUT), člen
Motyčka Arnošt, doc. Ing., CSc. (Mendelu), člen
Sekanina Lukáš, prof. Ing., Ph.D. (DCSY FIT BUT), člen
Zbořil František, doc. Ing., Ph.D. (DITS FIT BUT), člen
Citation
KŘÍŽOVÁ, Martina. Analýza genomických dat s využitím algoritmu BLAST. Brno, 2008. Bachelor's Thesis. Brno University of Technology, Faculty of Information Technology. 2008-08-26. Supervised by Jaša Petr. Available from: https://www.fit.vut.cz/study/thesis/6644/
BibTeX
@bachelorsthesis{FITBT6644,
    author = "Martina K\v{r}\'{i}\v{z}ov\'{a}",
    type = "Bachelor's thesis",
    title = "Anal\'{y}za genomick\'{y}ch dat s vyu\v{z}it\'{i}m algoritmu BLAST",
    school = "Brno University of Technology, Faculty of Information Technology",
    year = 2008,
    location = "Brno, CZ",
    language = "czech",
    url = "https://www.fit.vut.cz/study/thesis/6644/"
}
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