Thesis Details

Interpretace dat z biočipů

Bachelor's Thesis Student: Ludwig Petr Academic Year: 2007/2008 Supervisor: Smrž Pavel, doc. RNDr., Ph.D.
English title
Microarray Data Interpretation
Language
Czech
Abstract

This Bachelor thesis explains the basics of biochip or microarray data interpretation, starting with short introduction to genetics, especially genetic information significance evaluating. The focus was set mainly on the set of scripts transforming and analyzing the sample data. The data used in this thesis are a result of biochip analysis of the Colon Tumor tissues. The secondary result represents disclosing the main marker for this particular type of cancer, the primary result is evaluation of marker significance in the context of signaling pathways. The resulting pathways are sorted by relevance.

Keywords

biochip, microarray, signaling pathways, gene ontology, Desmin, bioinformatics, genetics, genes expression, downregulation, upregulation, KEGG, BioRuby, Ruby, cancer, tumor, colon, DNA, RNA, nucleus acids

Department
Degree Programme
Information Technology
Files
Status
defended, grade C
Date
12 June 2008
Reviewer
Committee
Černocký Jan, prof. Dr. Ing. (DCGM FIT BUT), předseda
Herout Adam, prof. Ing., Ph.D. (DCGM FIT BUT), člen
Lukáš Roman, Ing., Ph.D. (DIFS FIT BUT), člen
Ráček Jaroslav, RNDr., Ph.D. (FI MUNI), člen
Vojnar Tomáš, prof. Ing., Ph.D. (DITS FIT BUT), člen
Zbořil František, doc. Ing., Ph.D. (DITS FIT BUT), člen
Citation
LUDWIG, Petr. Interpretace dat z biočipů. Brno, 2008. Bachelor's Thesis. Brno University of Technology, Faculty of Information Technology. 2008-06-12. Supervised by Smrž Pavel. Available from: https://www.fit.vut.cz/study/thesis/7027/
BibTeX
@bachelorsthesis{FITBT7027,
    author = "Petr Ludwig",
    type = "Bachelor's thesis",
    title = "Interpretace dat z bio\v{c}ip\r{u}",
    school = "Brno University of Technology, Faculty of Information Technology",
    year = 2008,
    location = "Brno, CZ",
    language = "czech",
    url = "https://www.fit.vut.cz/study/thesis/7027/"
}
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