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Gene Ontology Driven Feature Filtering from Microarray Data

ŠILHAVÁ Jana a SMRŽ Pavel. Gene Ontology Driven Feature Filtering from Microarray Data. In: Znalosti 2010. 9th Annual Conference, Jindřichův Hradec. Jindřichův Hradec, 2010, s. 263-266. ISBN 978-80-245-1636-3.
Název anglicky
Gene Ontology Driven Feature Filtering from Microarray Data
Typ
článek ve sborníku konference
Jazyk
čeština
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Abstrakt
Microarray data is high-dimensional and noisy. Dimension reduction, i.e. selecting a small number of genes, is an effective way to improve mining efficiency. We propose a novel approach that integrates gene ontology knowledge at the level of feature selection into microarray data to improve binary class prediction. The advantage of this filtering approach lies in considering gene-to-gene relations and selecting more meaningful features comparing to the methods evaluating genes in isolation. In addition, gene ontology knowledge can overcome the limitations of noisy microarray data. Our approach is evaluated on a real benchmark dataset.
Rok
2010
Strany
263-266
Sborník
Znalosti 2010
Řada
9th Annual Conference, Jindřichův Hradec
Konference
Znalosti 2010, Jindřichův Hradec, CZ
ISBN
978-80-245-1636-3
Místo
Jindřichův Hradec, CZ
BibTeX
@INPROCEEDINGS{FITPUB9126,
   author = "Jana \v{S}ilhav\'{a} and Pavel Smr\v{z}",
   title = "Gene Ontology Driven Feature Filtering from Microarray Data",
   pages = "263--266",
   booktitle = "Znalosti 2010",
   series = "9th Annual Conference, Jind\v{r}ich\r{u}v Hradec",
   year = 2010,
   location = "Jind\v{r}ich\r{u}v Hradec, CZ",
   ISBN = "978-80-245-1636-3",
   language = "czech",
   url = "https://www.fit.vut.cz/research/publication/9126"
}
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